9:00-10:00 • Smurfit institute of genetics - Atrium
Sign in and coffee/pastries
10:00-10:15 • Hamilton building - MacNeill theatre
Welcome and opening remarks
10:15-11:00 • Hamilton building - MacNeill theatre
Keynote 1: Dr Nikolaos Vakirlis - Chair Amy Ó Brolcháin
Session 1: Evolution and population genetics - Chair Dr Elle Loughran
From Similarity to Specificity: Dissecting Functional and Mutational Landscapes of Paralogous Genes
Olivier Dennler | 11:00-11:12
Gene gain, sequence evolution, and synteny shape the diversification of Lepidoptera
Peter Mulhair | 11:12-11:24
Genomic testing of hypotheses on the origins of the Grecìa Salentina population and language
Martina Gulì | 11:24-11:36
Genomic characterisation of recurrent Mycobacterium avium isolates from chronically infected patients reveals patterns of within-host evolution
Aaron Walsh | 11:36-11:42
What's in a Name? Tracing the Structural and Functional Evolution of the Ligand of Numb Protein X Family
Leah Gabrielle Erwin | 11:42-11:48
Evolution of histone mRNA 3' end processing machinery in eukaryotes
Bin Zhao | 11:48-11:54
CloudCIX talk
11:54-12:00
12:00-12:10
Break
Session 2: Medical genetics - Chair Corey Alwell
The presence of a secondary species alters P. aeruginosa ciprofloxacinresistance evolution in the cystic fibrosis lung
Sadhbh Dodd | 12:10-12:22
Blood DNA Methylation Modifications in Response to Opioid Exposure in a Rodent Model
Nicole Glendinning | 12:22-12:34
Development of a blood-based transcriptional biosignature for the detection of cattle infected with Mycobacterium bovis, which causes bovine tuberculosis
David MacHugh | 12:34-12:46
Single-Cell Transcriptomic Decoding of B Cell Diversity in IgA Vasculitis Reveals a Glycosylation-Dysregulated Naïve Subset.
Joao Carlos Batista-Liz | 12:46-12:52
Quantifying Haploinsufficiency in Tumour Suppressor Genes: a Cancer Hallmarks-Based Functional Screen
Elle Loughran | 12:52-12:58
Transcriptomic Dysregulation of Bone Marrow Mesenchymal Stromal Cells in Type 2 Diabetes Mellitus
Jingyan Wang | 12:58-13:04
Concurrent session: Posters
13:05-14:30 • Smurfit institute of genetics - Atrium: Evolution and population genetics
Posters and coffee/lunch
13:05-14:30 • Moyne institute: Medical genomics & Methods and tools
Posters and coffee/lunch
Concurrent session: ELIXIR
13:30-14:30 • Smurfit institute of genetics - Dawson room
VIBE & ELIXIR-IE breakout session
14:35-15:20 • Hamilton building - MacNeill theatre
Keynote 2: Dr. María Ávila-Arcos - Chair Catherine Butt
Session 3: Evolution and population genetics - Chair Tomas Gomes
Characterisation of diverse global ancestries among participants of the UK Biobank illustrates the immigration history of Great Britain in the 20th century
Fiona Pantring | 15:20-15:32
Homology-Based miRNA Annotation and Evolution Across Mammals
Sarahjane Power | 15:32-15:44
Building a Placenta: Roles for Syncytin-Like Retroviral Envelopes of Livebearing Fish
Amy Ó Brolcháin | 15:44-16:56
Natural knock-outs of human genes are more frequently observed in genes with paralogs.
Carlos Vivas Rodríguez | 15:56-16:02
A Duplicate-Resolved Paddlefish Genome Provides Insights into the Mechanisms of Rediploidization and Hox Cluster Evolution
Dearbhaile Casey | 16:02-16:08
The Genomics of an Irish Hunter-Gatherer Community
Corey Alwell | 16:08-16:14
Developing research infrastructure to empower Irish genetics and genomics innovation under EHDS
Aedín Culhane | 16:14-16:20
16:20-16:30
Break
Session 4: Methods and Tools - Chair Róisín Long
Development of a Nextflow Pipeline for Consensus MHC Class I Genotyping within a Cloud-Based Neoantigen Prediction Workflow
Kevin Ryan | 16:30-16:42
AMRcast: A machine learning framework to predict AMR phenotypes from genomic functional annotations
Lucy Dillon | 16:42-17:54
PyamilySeq: Transparent and interpretable gene (re)clustering and pangenomic inference highlights the fragility of conventional methods
Nicholas Dimonaco | 16:54-17:06
CarbaSnake: a clinically orientated, open-source workflow for the genomic characterisation of Carbapenemase-producing Enterobacterales (CPE)
Emily Cronin | 17:06-17:12
A predicted cancer dependency map for paralog pairs
Narod Kebabci | 17:12-17:18
Predicting drug resistance to synthetic lethal therapies in cancer
Metin Yazar | 17:18-17:24
Evaluation of partitioning algorithms for trustworthy out-of-distribution evaluation of machine learning models in biochemistry
Raúl Fernández Díaz | 17:24-17:30
17:30-17:40 • Hamilton building - MacNeill theatre
Closing remarks and awards - Chair Dr Máire Ní Leathlobhair
18:00 • The Pav
Social event with Roots in Tune